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These data suggest that glucagon agonism provides additional liver fat reducing efficacy beyond what is expected from weight loss alone

Changes in Bowel Habits: You may experience temporary constipation or diarrhea as the gut adjusts to the timing shift

doi: 10.1186/s13052-022-01319-1 73 CrinASchiaffiniRCiampaliniPSperaSBeccariaLBenziFet al

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In an 8-week open-label trial, a group of researchers evaluated the effect of Clostridium butyricum MIYAIRI 588 (CBM588) in patients with treatment-resistant MMD in an open-label study (Miyaoka et al., 2018)