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If single morning administration produces satisfactory results, adding complexity provides no advantage

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the drug was discontinued in 3.6% of the persons in the CagriSema arm compared to 1.3% in the comparators' arms, and observed gastrointestinal adverse events per patient per year were 2.8 with CagriSema versus 2.6 with semaglutide 2.4 mg monotherapy [125]