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Women with PCOS have increased risk of classic coronary heart disease risks such as hypertension, increased weight, diabetes mellitus and dyslipidemia, but also non-classic cardiovascular risks factors like mood disorder, depression and anxiety

The extremely low blood pressure effect was seen in rats

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Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships, in Feingold K.R., Anawalt B., Boyce A., Chrousos G., De Herder W.W., Dhatariya K., Dungan K., Hershman J.M., Hofland J., Kalra S., Kaltsas G., Koch C., Kopp P., Korbonits M., Kovacs C.S., Kuohung W., Laferrre B., Levy M., McGee E.A

This peptide has been suggested to exhibit its potential primarily on fibroblasts, responsible for maintaining and growing the extracellular matrix (ECM) components surrounding the cells