In addition, although the GOLDEN 3 and 4 studies allowed the inclusion of patients with comorbidities, it must be noted that patients with severe comorbidities (e.g., unstable CVD and/or long QT syndrome) were excluded 7

TIER 1 (34mg total) $299 total for 8-10 week supply Monthly cost breakdown: $119-$149 based on weekly dose Recommended if new to treatment or for those on 2-4mg/week TIER 2 (68mg total) $339 total for 8-10 week supply Monthly cost breakdown: $135-$169 based on weekly dose Recommended for those on 5-8mg/week TIER 3 (102mg total) $369 total for 8-10 week supply Monthly cost breakdown: $147-$184 based on weekly dose Recommended for those on 9-12mg/week TIER 4 (136mg total) $399 total for 10 week supply Monthly cost breakdown: $159 based on weekly dose Recommended for those on 13mg/week and up EXTENDED PLANS Foundation Plan (85mg total) $425 total for 3-4+ supply Monthly cost breakdown: $106-141 Recommended if new to treatment or for those on doses up to 7mg/week Momentum Plan (153mg total) $500 total for 3-4+ supply Monthly cost breakdown: $125 Recommended for doses up to 10mg/week Elevate Plan (204mg total) $550 for 3-4+ month supply Monthly cost breakdown: $137 Recommended for doses of 11mg/week & up MONTHLY PLANS Monthly Starter Dose $190 total for one month supply Recommended if new to treatment or for those on doses of 4mg/week or less Monthly Mid Dose $205 total for one month supply Recommended for doses up to 8.5mg/week Monthly Advanced Dose $225 total for one month supply Recommended for doses of 9-12.5mg/week Monthly Advanced Plus Dose $240 total for one month supply Recommended for doses of 13mg/week and up Southend Pharmacy - Tirzepatide/B6 Injection Up to 90 days BUD

: Li J, Liu L, Weng J, Yin TL, Yang J, Feng HL
In the era of precision prevention, together with updated pooled cohort equations such as the Predicting Risk of Cardiovascular Disease Events (PREVENT) calculator [15, 16] that distinguish the individuals risk of atherosclerotic cardiovascular disease (ASCVD) and/or heart failure (HF), primary preventative strategies could be tailored in accordance to the individuals risk profile [17,18,19]
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