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doi: 10.1017/S000711451900148X 90

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In addition, using a time-dependent Cox regression analysis with SGLT2i use categorized by randomized treatment as a fixed factor yielded HRs for the primary outcome of 0.87 (95% CI, 0.711.06) for those using SGLT2i during the study (either from baseline or initiated during the study) and 0.83 (95% CI, 0.730.95) for those who never used SGLT2i throughout the study (Table S6)

Whether you are just starting out or adjusting your protocol, knowing how to calculate these numbers correctly is critical for safety and effectiveness

Doses above three grams daily are not supported by better outcomes and can increase side effects