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It is symptomatic of the governments failure to properly manage public monies, ultimately affecting the delivery of development projects meant to benefit our communities and the rural majority

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Microbiota and thyroid interaction in health and disease

We hypothesize that SAC inhibits the E3 ubiquitin ligase activity of KEAP1 through interaction, thereby blocking the ubiquitination-mediated degradation of NRF2, stabilizing the NRF2 protein, and activating the transcription of various protective genes, including antioxidant enzymes