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Two trials reported data for serum vitamin B 12 levels

The neuroprotective effect of GLP-1R agonists is that it can either directly/locally cause neuroprotection by acting on neuronal tissue or indirectly/systemically cause neuroprotection by improving glycemic control and treating existing insulin resistance (Figure 3) (Fiory et al., 2019

Also in kidney, localization of GLP-1 receptor is under investigation, but it is thought to be expressed in vascular smooth muscle cells and immune cells in kidney [43]

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