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Pioneer 1: Randomized clinical trial of the efficacy and safety of oral semaglutide monotherapy in comparison with placebo in patients with type 2 diabetes

With the obesity epidemic contributing to rising rates of diabetes, heart disease and other chronic conditions, GLP-1 therapies represent a potential turning point in the fight against these diseases

According to a joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society, a daily protein intake of 1.21.6 g/kg adjusted body weight, should be considered in individuals initiating GLP-1RA therapy, particularly when caloric restriction is prescribed

Kohen, I

This preparatory phase helps patients build habits such as slowing down during meals, emphasizing protein first, reducing sugary drinks, and maintaining hydration