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Study is needed to elucidate the pathophysiology to further understand why most patients have no hypoglycemia after gastric bypass, some have mild to moderate PGBH, and a small percentage have severe PGBH with debilitating neuroglycopenia unresponsive to dietary changes and medications
PLoS ONE 8 , e84569 (2013)
In these experiments, we pre-treated IMG microglial cells with exendin-4, Twincretin, LY329, or Triagonist, then stimulated the cells to adopt a pro-inflammatory phenotype using LPS
Calocurb may also be useful as a plant-based alternative that still supports appetite control when paired with the right lifestyle strategies
"It's a worthwhile discussion for the patient and provider to really think about what is going to help them stay on the medication longer," says Watanabe
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