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These are peptide-based drugs manufactured through chemical synthesis or recombinant methods not large biologic proteins like monoclonal antibodies, but structurally complex enough that the manufacturing process itself represents a barrier to generic entry independent of the patent estate

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Miao H, Wu XQ, Wang YN, Chen DQ, Chen L, Vaziri ND

Some patients choose to restart tirzepatide at maintenance-level doses (lower than treatment-level doses) if they experience weight regain signals