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This difference in absorption rates explains why most clinical studies have focused on injectable forms of the medication

The investigators conducted a multicenter, double-blind, placebo-controlled, active-controlled phase 3a trial (ClinicalTrials.gov ID: NCT05567796) evaluating the efficacy and safety of the combination of semaglutide and cagrilintide in adults without diabetes with a body-mass index (BMI) of greater than or equal to 30 or greater than or equal to 27 with at least one obesity-related complication

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Nausea or transient gastrointestinal discomfort during initial dosing

Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA secretory phospholipase A(2)