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GLP-1 is released primarily from the ileum and colon in the response to food intake

Weeks 13 through 16: 8 mg weekly What is happening: Full triple-agonist effects are now substantially engaged

N Engl J Med 2021;384:989-1002.ArticlePubMed 33

Briefly, RNAs were treated with DNase I (Roche) to remove genomic DNA, incubated with 50 ng of random hexamers and 0.5 l of 10 mM dNTPs for 5 min at 65 C