doi: 10.1161/CIRCULATIONAHA.125.074545 Summary Keywords cardiovascular outcomes, SGLT2 inhibitors, GLP-1 agonists, combination therapy, heart failure, renal outcomes Citation Aristizbal-Colorado D, Corredor-Rengifo D, Sierra-Castillo S, Lpez-Corredor C, Vernaza-Trujillo D-A, Weir-Restrepo D, Izquierdo-Condoy JS, Ortiz-Prado E, Rico-Fontalvo J, Gmez-Mesa J-E, Abreu-Lomba A and Rivera-Martnez W-A (2025) A decade of progress in type 2 diabetes and cardiovascular disease: advances in SGLT2 inhibitors and GLP-1 receptor agonists a comprehensive review
Understanding these distinctions helps patients and providers engage in informed conversations, rather than viewing the peptides as competing or interchangeable options
There is, therefore, a clear need for interventions that address the stigma associated with using GLP-1s for weight loss
Importantly, several NDD-associated genes, including GBA, GRN, and ATP13A2, are shared with lysosomal storage disorders, reinforcing lysosomal integrity as a critical determinant of neuronal health
ABCC8 gene: The KCNJ11 gene (above) encodes one subunit of the ATP-sensitive potassium channel