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The gold standard treatments are dopamine replacement with dopaminergic medications or brain stimulation
2008, titled Anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression: a [11C]DASB PET study, in patients, low serotonin transporter availability correlated with high anxiety
10.1007/s00726-011-1206-6 Summary Keywords Pichia pastoris, peptide-crossing-blood-brain-barrier, delta-sleepinducing peptide, neurotransmitter balance, mouse model, PCPA-induced insomnia Citation Mu X, Qu L, Yin L, Wang L, Liu X and Liu D (2024) Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models
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