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Estrogen primarily targets mitochondrial function, vascular health, neuronal energy metabolism, and the redistribution of adipose tissue

Some people report meaningful appetite suppression and weight loss with sublingual formulations

With its usual fuel source running low, your body starts breaking down fat into ketones and burning those for energy instead

Supplementation should always be integrated into a broader protocol that includes aggressive pacing to manage post-exertional malaise, careful symptom tracking, dietary modifications to support histamine clearance, and ongoing medical care from specialists who truly understand the interconnected nature of neuro-immune diseases

But there are other options available for those who want to try a different approach