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To review: a peptide is a short chain of amino acids that is linked by peptide (carboxyl group) bonds after a condensation reaction, removing H2O

A comparison of our Sas Pcob structure with other photocobilin proteins (predicted structures obtained from the recently published Alphafold2 database 26 ), shows they can be divided into three main groups depending on the location of the AdoCbl-binding domain at either the N- or C-terminus, and whether they contain the additional output domain in the fused proteins (Supplementary Figs

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