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Besides, circRNA_09505 can promote AKT1 expression via regulating the IB/NF-B signaling pathway in macrophages, the most interesting is circRNA_09505 knockdown significantly alleviates arthritis and inflammation in CIA mice (278)

However, as these aspects have been demonstrated to affect neural circuits and key events involving in the etiology of epilepsy [152], it requires further exploration for precise manipulation of epilepsy treatment in the future

Together, these components form the extracellular structures, which trap and neutralize pathogens