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By activating melanocortin receptors in pigment cells, the spray aims to enhance tanning responses when exposed to UV rays

A newly observed adverse event in Phase 2 and 3 investigational trials dysesthesia (abnormal skin sensations) was reported in approximately 20% of participants at the highest doses and has not been a notable feature of mono- or dual-agonist predecessors, suggesting this may be GCGR-mediated

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Theres also some evidence for a few other nutrients that specifically affect GLP-1: Fiber : In rats and dogs, at least, dietary fiber increases GLP-1 production

[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Jimnez A, Casamitjana R, Viaplana-Masclans J, Lacy A, Vidal J