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doi: 10.1016/j.jacbts.2018.09.004 126 RizzoMNikolicDPattiAMManninaCMontaltoGMcAdamsBSet al

Compounded medications are regulated and compounding pharmacies are licensed and inspected by Boards of Pharmacy, but the FDA has not evaluated the medications for safety, quality, or efficacy

The following guidance reflects current clinical recommendations and patient safety advice

Some of the newer drugs also mimic GIP (glucose-dependent insulinotropic polypeptide) or even glucagon receptors , offering an even broader metabolic impact

Clinical studies have found these medications may: Improve insulin sensitivity Support healthier blood sugar regulation Improve certain cardiovascular risk factors Reduce inflammatory signaling Improve lipid profiles in some patients Researchers continue to investigate whether some of these benefits may occur independently of weight loss, although many questions remain about how these medications should be used outside their approved indications