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The very low rate constants for direct, glutathione-independent dithiol-disulfide exchange reactions between glutaredoxins and roGFP2 or other protein(S 2 )/protein(SH) 2 couples (despite favorable thermodynamics) are a prerequisite and great advantage for reliable redox measurements in vivo

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Talbert ME, Langefeld CD, Ziegler J, et al

Factors That Influence Your Results Taking glutathione is not a "magic fix" that works overnight

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In the presence of UVR, reduced folates may undergo irreversible oxidative cleavage into by-products of pteridine and p-aminobenzoylglutamate, both of which lack vitamin activity