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Recombinant human insulin-like growth factor-I enhances whole body protein anabolism and significantly diminishes the protein catabolic effects of prednisone in humans without a diabetogenic effect

B12 is a marker, not a cause, and elevated levels should be considered alongside other clinical signs and tests

However, maintaining B12 status during aggressive weight loss prevents the potential complication of developing new deficiencies while correcting obesity-related metabolic dysfunction

serious events have not been documented in limited human observations

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