This can cause stomach paralysis, which is an incredibly painful health complication that would require gastric bypass surgery to fix
I find that for people who have the potential to start a family or to continue their family, it's a very high-risk medication, says Fishman, Thus, the FDA recommends that if you are of child-bearing potential, use a highly-effective method of birth control and talk to your doctor now about weaning off the medication if you consider getting pregnant in the near future
It has been proven that glucagon-like peptide-1 receptor (GLP-1R) agonists control blood glucose concentrations through a multitude of mechanisms, such as increased satiety, slow stomach emptying, decreased glucagon secretion, and increased insulin synthesis/secretion
The STEP 4 trial showed that stopping semaglutide leads to regaining approximately two-thirds of the lost weight within a year
Exenatide, the first GLP-1 receptor agonist, was approved in 2005, followed by the development of extended-release versions such as liraglutide and semaglutide (Furman 2012)
