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In addition, Ghr expression was decreased in the liver of LPD animals (Figure 3E, Table 3), consistent with a GH-resistant state [53]

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After 6 months of adherence to creatine and arginine hydrochloride therapy, the patients Gross Motor Function Classification System score (GMFCS) improved

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Chronic inflammation leads to cartilage destruction, bone erosion, and progressive joint deformity

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