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Scand J Gastroenterol 47(1):4348

Evidence of lipid dysregulation and energy issues was also observed in plasma, with elevated odd-chain acylcarnitines in GW agent-exposed mice, and in veterans with GWI, relative to their respective controls

94 It is important to note that SIRT1 regulation of lipid metabolism is tissue-specific and dependent on metabolic conditions

Key parameters such as lipid-to-drug ratio, bilayer composition, vesicle size distribution, and surface modifications (e.g., PEGylation or targeting ligands) are systematically adjusted

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