Patients with a history of gastrointestinal issues or those who are sensitive to certain foods may benefit from tailored enzyme supplementation
Enzymes involved in this process include cystathionine synthase (CBS), cystathionine -lyase (CSE), and 3-mercaptopyruvate sulfur transferase (MST) (Figure 1)
If gastrointestinal symptoms are problematic at night, consider: Eating your evening meal at least 34 hours before bedtime Consuming smaller, more frequent meals throughout the day Avoiding rich, fatty, or spicy foods in the evening, which may exacerbate reflux or nausea Address gastrointestinal side effects proactively
Tirzepatide (Mounjaro) Tirzepatide, marketed as Mounjaro in the UK, remains the most effective weight-loss injection based on clinical trial data
If you have modest weight loss goals (1525 pounds), a history of side effects with medications, or simply prefer a gentler approach, starting low is clinically sound and cost-effective