It does so by blocking the enzyme that triggers melanin production in the skin
The optimal approach often must be determined empirically
Coverage varies by plan, employer benefits, diagnosis, medication formulary, and medical necessity rules
Thus, a loss of estradiol post-menopause, may contribute to the development of obesity, and systemic and cerebral insulin resistance ( This review describes the physiological and pathophysiological mechanisms that govern the actions of estradiol on food intake and energy expenditure during the menstrual cycle ( Menstrual cycle and appetite control: Implications for weight regulation The CNS, particularly the hypothalamus, plays a key role in homeostatic feeding
The most common side effects are gastrointestinal, like nausea, diarrhea, vomiting, or constipation