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Weibull distribution modeling ( = 0.59, 95% CI 0.580.61) indicated these NAEs are likely to occur during initial treatment phases (Table 2, Fig

These tissue changes, caused by repeated injections in the same location, create areas of altered fat distribution that may lead to unpredictable drug uptake

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Some can cause nausea, which, of course, is also a common side effect of GLP-1s

In trials, tirzepatide and retatrutide had slightly higher rates of GI effects than semaglutide due to the additional pathway activation