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Some protocols recommend gradual titration up to 20 to 45 mg per day if no significant side effects appear

standard (SAGM) was confirmed that RBCs stored in the former additive are more metabolically active, owing to the beneficial effects of higher pH on the enzymatic activities of PFK, BPGM and G6PD, the rate-limiting enzymes of glycolysis, the Rapoport-Luebering shunt and the pentose phosphate pathway 46

Increasing insulin sensitivity : These agonists can improve the bodys responsiveness to insulin

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