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Emphysema can sometimes present as chronic obstructive pulmonary disease (COPD), currently the fourth leading cause of death worldwide, with an estimated prevalence of 10% (4)

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It also notes rare cases of pancreatitis and gallbladder disease that require medical monitoring, and describes black-box warnings tied to a personal or family history of medullary thyroid cancer and multiple endocrine neoplasia type 2

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