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Topline Eli Lilly, the GLP-1 maker behind Mounjaro and Zepbound, said it would file for Food and Drug Administration approval of its powerful retatrutide weight-loss drug after studies found participants lost an average of nearly 56 pounds after 80 weeks on the medication

On top of that, one of the biggest complaints about GLP-1s, when taken according to the standard doses approved by the FDA is that they cause side effects such as nausea, diarrhea and fatigue

Recently, over-the-counter dietary supplements that dont require a prescription have hit the market, including Kourtney Kardashians Lemme GLP-1 Daily, which claims to naturally boost GLP-1 levels in the body to reduce hunger and support healthy weight management