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Moreover, injections of IM and IV might be somewhat unpleasant

Eve Roberts, writing in the AASLD Practice Guidelines for Wilson Disease , emphasized that "any exogenous copper load in a patient with compromised biliary excretion has the potential to accelerate hepatic copper accumulation" [2]

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The results showed that ATT-I treatment ranging from 6.25 to 100 M for 24 h didnt induce the reduction of cell viability, whereas ATT-I at 200 M significantly inhibited the cell viability (Figure 10A)

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