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These patterns become valuable information for adjusting your approach

This temporary disruption typically resolves as your system adjusts, but practical strategies can ease the transition: maintain consistent sleep and wake times, avoid large meals within 3 hours of bedtime (already easier on GLP-1), and limit screen time 30 minutes before sleep

Guidelines recommend discontinuing therapy if a patient does not achieve at least 5% weight loss after 3 months on the maintenance dose, as benefits are unlikely to outweigh risks in such cases