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Shen et al., 2012

Mitochondrial function in liver cells is resistant to perturbations in NAD(+) salvage capacity

Potential Research Applications Epithalon is currently being explored in research settings for its role in: Telomere Support: Investigated for its potential impact on telomerase activity and cellular lifespan

Last reviewed: July 20, 2026 Last updated: July 20, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

A major developmental study of compulsivity trait using magnetisation transfer (MT) imaging to quantify network connectivity in adolescents found that a composite compulsivity score (OCI plus Padua scale) was related to reduced growth of the MT trajectories in fronto-striatal circuity, most markedly in dorsolateral and dorsomedial prefrontal regions, including the SMA, consistent with our findings in this region, and further supporting a possible causal role of the changes in neural network function in OCD 2