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Ghrelin, leptin, and glucagon-like peptide-1 (GLP-1) help manage hunger or appetite

This suggests that the drug doesn't merely shift the average lifespan but might help more mice reach an older age than otherwise possible

DSIP is proposed to interact with components of the MAPK cascade via this mechanism providing a potential molecular basis for its glucocorticoid-related biology, anti-proliferative activity, and stress-protective effects

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[DOI] [PubMed] [Google Scholar] 200.Zemba Cilic A., Zemba M., Cilic M., Balenovic I., Strbe S., Ilic S., Vukojevic J., Zoricic Z., Filipcic I., Kokot A., et al