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Acromegaly is an endocrine condition, which is manifested with excess secretion of pituitary GH accompanied by an elevated level of circulatory IGF-1 (273)

The first sample was dissolved in methanol with 0.1 mL of 50 % of the SSA and the second sample in an ammonium buffer pH 3.5 [H 2 O/ACN (90:10) (v/v) + 1 mM NH 4 (CH 3 COO)] with CH 3 COOH

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