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In December 2020, the FDA issued approval for the drug to be used in adolescents as young as 12 years old with a body weight above 132 pounds (60 kg) with obesity

Cholesterol interaction profiles were calculated using PyLipID (29) with a cut-off of 0.7 nm

High consumers reduced their intake from 23 to 8 units per week on average, and low consumers saw their intake halve

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