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In particular, when the serum and CSF of PD patients were compared with those of controls, altered levels of sphingolipids (e.g., sphingomyelins and ceramides), phosphatidylcholines, phosphatidylethanolamines and docosahexaenoic acid (DHA) were observed

Evidence level key: (1) Human observational: Cohort/cross-sectional studies with metabolomic/microbiome profiling