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[13] Mannitol acts by osmosis to enhance urine production and is thought to prevent myoglobin deposition in the kidney, but its efficacy has not been shown in studies, and there is a risk of worsening kidney function

Ridker PM, Bhatt DL, Pradhan AD, Glynn RJ, MacFadyen JG, Nissen SE (2023) Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials

Use within 14-21 days

Increased production of activated B cells can increase TNF- in the bone marrow, resulting in the differentiation of marrow stem cells into osteoclasts

Among these, fat embolism syndrome stands out as a potential complication that sometimes has critical consequences