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The obtained Cy5.5-labelled TP-10@CaP-CTP and TP-10@CaP nanoparticles were collected by centrifugation, washed with deionized water and ethanol, and dispersed in PBS for further in vivo imaging

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29 In terms of improving reproductive function, studies have shown that GLP-1RA can reduce total testosterone (T) and free T levels in obese PCOS patients, thereby alleviating hyperandrogenism, improving menstruation, and increasing fertility rates

GIP receptor agonism, a core component of tirzepatide alongside GLP-1 agonism, also promotes glucose-dependent insulin secretion and improves insulin sensitivity

Some people may need to stay on a lower dose for two months instead of one, while others may need specific advice on managing underlying digestive sensitivities