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Schauer PR, Kashyap SR, Wolski K, Brethauer SA, Kirwan JP, Pothier CE, Thomas S, Abood B, Nissen SE, Bhatt DL

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In preclinical models, researchers are exploring effects on endothelial function, blood pressure, lipid profiles, and inflammatory biomarkers

Ongoing phase 3 programs (such as the TRIUMPH and TRANSCEND series) continue to evaluate these outcomes in larger, longer-term settings, including direct comparisons with tirzepatide