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doi:10.1017/S1461145707008401 Bell CJM, Mehta M, Mirza L, Young AH, Beck K

Herein, we apply an integrative approach to study the immunometabolism of pre- and post-infusion CD19-CAR T cells of patients with relapsed/refractory B-ALL

None of these has direct trial data as a plateau-rescue tool

We call these molecules free radicals

The GSH tripeptide (- L-glutamyl-L-cysteinyl-glycine), the most abundant water-soluble non-protein thiol in the cell (110 mM) is fundamental for life by (a) sustaining the adequate redox cell signaling needed to maintain physiologic levels of oxidative stress fundamental to control life processes, and (b) limiting excessive oxidative stress that causes cell and tissue damage