GLP-1 drugs dont just reduce the desire for alcohol
Targeting cerebral incretin and insulin receptors appears to show promise for neurodegenerative conditions, perhaps through neuroprotective mechanisms including reducing cell death and inflammation whilst enhancing neurogenesis
Ishibashi Y, Matsui T, Takeuchi M, Yamagishi S: Glucagon-like peptide-1 (GLP-1) inhibits advanced glycation end product (AGE)-induced up-regulation of VCAM-1 mRNA levels in endothelial cells by suppressing AGE receptor (RAGE) expression
Semaglutide and liraglutide serve as examples of GLP-1 receptor agonists, while sitagliptin and saxagliptin are commonly used DPP-4 inhibitors
its asset Exl-111, strengthening Novartis immunology strategy in food allergy & other IgE-driven diseases Total Revenue: $58.14B Founded Year: 1891 Total Employees: 74,000 Headquarters: New Jersey, United States Market Cap: $303.31B Stock Exchange: NYSE Merck & Co