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Important contraindications include concurrent use of nitrates or nicorandil (used for angina) and riociguat (for pulmonary hypertension) due to the risk of severe hypotension

By contrast, the interaction of mitofusin 1 (Mfn1) and 2 mediates OMM fusion, while optic atrophy 1 (OPA1) regulates IMM fusion (Ni et al., 2017)

Studies have shown that Nrf2-regulated ferroptosis plays important roles in the treatment and protection against ALI

Catalase (CAT), peroxidase (POD), glutathione reductase (GR), and superoxide dismutase (SOD) are enzymes that have antioxidant effects in biological and biochemical systems