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Am J Med 1961;31:532-46

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Soluble fiber (found in oats, bananas, and apples) can paradoxically help some patients by forming a gel that slows intestinal transit, though insoluble fiber (wheat bran, raw vegetables) may worsen symptoms initially and should be introduced slowly

A patent was subsequently sought for silymarin as a specialized treatment for liver issues by the German herbal medicine manufacturer Madaus after realizing its potential

Its unique mechanism of action, effectiveness in improving glycemic control, and added benefit of weight loss, make it a valuable tool in the management of type 2 diabetes