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Another key player is the p53 gene, which is now recognized as a cancer suppressor and important regulator of microenvironment in the stem cell niche [ 13 ]

It sounds like a minor chemical tweak, but the functional implications are massive

Compared to H1271K, the T1273A mutant showed more post-ER staining in the perinuclear region, and this colocalised with the cis-Golgi marker GM130, consistent with a protein that is leaving the ER but then being recycled by binding COPI (Supplementary Fig

eating control

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