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Alterations in G6PD levels may promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in a human melanoma xenograft model, and G6PD regulated STAT3 activity via the NADPH oxidase 4-NADPH-ROS-proto-oncogene tyrosine protein kinase/protein-tyrosine phosphatase 1D signaling pathway in A375 melanoma cells (69,70)

The observed reduction in glycerol may reflect increased utilization for gluconeogenesis and ketogenesis, or a decrease in lipolytic activity, metabolic pathways that could all impact the ability to sustain energy production during or between seizures 23

As people age, they produce less glutathione

Agrawal P, Bhagat D, Mahalwal M, Sharma N, Raghava GP (2021) AntiCP 2.0: an updated model for predicting anticancer peptides