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Therefore, it is not surprising that both ACE inhibitors and AT1 antagonists are effective in reducing OS on various cardiovascular diseases ( 5.1 Endothelial dysfunction Endothelial dysfunction and OS are inextricably linked in the pathophysiology of HTN, leading to vascular damage and elevated BP

And in the U.S., the widely accepted threshold for cost-effectiveness is $100,000 per QALY

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