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PMC 423392

As an analog of endogenous growth hormone-releasing hormone (GHRH), tesamorelin boasts a metabolism-stimulating activity that has led to its being approved as a treatment for lipodystrophy, or abnormal adipose fat accumulation associated with antiretroviral therapy for HIV.3 But this same activity can help non-HIV individuals shed abdominal fat of their own, while the peptides GHRH properties make it a suitable therapy for people looking to increase their lean mass

doi: 10.1056/NEJMoa1603827 13 MarsoSPBainSCConsoliAEliaschewitzFGJodarELeiterLAet al

However, its effects on gut motility and potential for constipation may influence symptoms in patients with pre-existing diverticular disease