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Additionally, 1,25(OH)D promotes the expansion and functional enhancement of regulatory T cells (Tregs), not only by directly upregulating FoxP3 and the anti-inflammatory cytokine IL-10, but also by inducing a tolerogenic phenotype in dendritic cells, thereby indirectly facilitating Treg induction [168,169,170,171,172,173].Furthermore, 1,25(OH)D inhibits the mTORC1 pathway and activates fatty acid oxidation, creating a favorable metabolic milieu for Treg differentiationa combined epigeneticmetabolic regulatory mechanism that is emerging as a central feature of Vitamin Dmediated immunomodulation [174, 175]

TID, Three times a day

This paper serves as a call to action for the food science community to embrace this paradigm shift and dedicate resources to further explore the vast, and largely untapped, potential of dietary hormesis

Track how your injection works throughout the week

I take one capsule at early morning on empty stomach