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Furthermore, although glucagon cells were not found receptor positive (Figure 3l and m), the somatostatin cells in the islets expressed GLP1R (Figure 3n and o)

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In contrast, the efficacy of combined treatments is less than ideal in tumors where MET imbalance results in reduced PD-L1 activity or when MET levels remain stable

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5 Conclusion In conclusion, the evolving landscape of MASLD treatment underscores the significant therapeutic promise of GLP-1RAs and dual or triple receptor agonists